NANOSIZED CUBOSOMAL THERMOGELLING DISPERSION LOADED WITH SAQUINAVIR MESYLATE TO IMPROVE ITS BIOAVAILABILITY: PREPARATION, OPTIMIZATION, IN VITRO AND IN VIVO EVALUATION

Nanosized Cubosomal Thermogelling Dispersion Loaded with Saquinavir Mesylate to Improve Its Bioavailability: Preparation, Optimization, in vitro and in vivo Evaluation

Khaled M Hosny1,2 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, EgyptCorrespondence: Khaled M HosnyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saud

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Consumption patterns before and during the COVID-19 pandemic among patients admitted to inpatient drug detoxification treatment: Results of two cross-sectional surveys from 2018 and 2021

BackgroundThe lockdown measures during the SARS-CoV-2 pandemic could have influenced drug consumption patterns of persons with drug use disorder, especially due to a reduced availability of drugs, an increased consumption of sedating substances as a coping strategy, ORG COCONUT SMILES or a shift to novel psychotropic substances (NPS) associated wit

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Panfacial trauma: management of a traumatic hemifacial avulsion and degloving injury with multiple maxillofacial fractures

Background: Cases of avulsion and degloving injuries of solitary areas of the face have been reported in the literature.However, complex traumatic degloving hemifacial injury with compound panfacial fractures is very rare.Rehabilitation of extensive degloving facial injuries poses a great challenge for surgeons.Surgery becomes more challenging if t

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